Heteroaromatic Lipoxin A4 Analogues

Synthesis and Biological Evaluation

Auteurs

• Colm Duffy

Séries

• Springer Theses

Paramètres

• 152 pages
• 6 heures de lecture

• Nonfiction

En savoir plus sur le livre

Colm Duffy's thesis explores stable lipoxin analogues' chemistry and biology. He synthesized a pyridine-containing LXA4 analogue in enantiomerically pure form and found that both epimers suppress key cytokines in inflammatory diseases, with the (R)-epimer being the most effective. He also developed a thiophene-containing analogue with notable biological activity, inspiring further research.

Achat du livre

• Année de publication: 2014
• Reliure: (souple)