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Several techniques are currently available for quantitatively studying global and regional blood flow and metabolism in the human brain. However, many scientists in clinical and research fields may be unfamiliar with the indications and limitations of these methods. The rapid evolution of modern imaging techniques and new tracers has contributed to confusion regarding the appropriate methods for diagnosing brain diseases. This skepticism and lack of knowledge may have hindered the broader adoption of these tools in clinical practice, potentially causing the significance of circulatory and metabolic parameters in central nervous system diseases to be overlooked. The contributions compiled in this text detail individual techniques, outlining their indications and limitations, with a focus on newer methods such as the atraumatic 133Xe technique, stable xenon tomography, and three-dimensional approaches like 133Xe single photon emission tomography and N-isopropyl-P23-iodoamphetamine. Additionally, positron emission tomography studies offer insights into function and metabolism, particularly concerning oxygen and glucose in specific brain regions. While nuclear magnetic resonance shows promise for studying metabolic parameters, accurate circulation measurements are currently not feasible.
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Cerebral Blood Flow and Metabolism Measurement, Alexander K. Hartmann, Siegfried Hoyer
- Langue
- Année de publication
- 1985
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- (rigide),
- État du livre
- Abîmé
- Prix
- 20,82 €
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