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N-based heterocyclic analogues and their application

Synthesis of quinoline analogues and their various application

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  • 64pages
  • 3 heures de lecture

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Focused on the synthesis of quinoline hybrid thiosemicarbazide derivatives using microwave irradiation, the book details their application in biological studies. The compounds showed promising results in docking studies, fitting well within protein cavities and achieving excellent G-scores. Additionally, molecular dynamics studies, pharmacophore analysis, and ADME-Tox evaluations were conducted to assess drug-likeness properties. The findings suggest that these synthesized molecules have potential as future hit compounds in drug discovery.

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N-based heterocyclic analogues and their application, Dhaval B. Patel

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Année de publication
2023
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