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The book presents a pioneering approach to synthesizing ethyl 6-amino-5-cyano-2-methyl-4H-pyran-3-carboxylate derivatives using water and ethanol as solvents, with urea as a novel catalyst. It highlights the efficiency of this method, achieving high yields in a short reaction time. Additionally, the findings indicate that aromatic aldehydes with electron-withdrawing groups yield better results and require less time compared to those with electron-donating groups, showcasing the significance of substituent effects in the synthesis process.
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Synthesis of Pyran Derivatives and Their Biological Activity, Dhaval B. Patel
- Langue
- Année de publication
- 2023
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- Titre
- Synthesis of Pyran Derivatives and Their Biological Activity
- Sous-titre
- DE
- Langue
- Anglais
- Auteurs
- Dhaval B. Patel
- Éditeur
- Scholars' Press
- Publié
- 2023
- Format
- souple
- Pages
- 56
- ISBN13
- 9786205521991
- Séries
- Mots clés
- Nonfiction, Science et Mathématiques, Sciences naturelles, Chimie
- Description
- The book presents a pioneering approach to synthesizing ethyl 6-amino-5-cyano-2-methyl-4H-pyran-3-carboxylate derivatives using water and ethanol as solvents, with urea as a novel catalyst. It highlights the efficiency of this method, achieving high yields in a short reaction time. Additionally, the findings indicate that aromatic aldehydes with electron-withdrawing groups yield better results and require less time compared to those with electron-donating groups, showcasing the significance of substituent effects in the synthesis process.