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Focusing on hot-melt extrusion (HME), this book explores its significant role in manufacturing and pharmaceutical research over the past thirty years. It highlights HME's effectiveness in creating solid dispersions for controlled and targeted drug delivery, enhancing bioavailability, and masking the taste of bitter APIs. The text covers various aspects, including equipment, processing technologies, and novel formulation designs, while presenting multiple case studies that demonstrate HME's applications in improving oral drug delivery systems.
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Hot-melt Extrusion, Mohammed Maniruzzaman
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- Année de publication
- 2013
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