C-H activation for asymmetric synthesis

Auteurs

• Françoise Colobert

Paramètres

• Autres manuels scolaires
• Manuels

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This handbook offers comprehensive coverage of a key topic in stereoselective chemistry, focusing on C-H activation in asymmetric synthesis. Authored by leading experts, it explores various aspects of stereoselective C-H functionalization, including outer-sphere and inner-sphere C-H bond activation, control of olefin geometry, and induction of chirality. The text discusses methods for introducing asymmetry during C-H activation or in subsequent steps. Organized into two parts, it first examines the asymmetric activation of C(sp3)-H bonds, detailing topics such as C(sp3)-H bond insertion by metal carbenoids and nitrenoids, and enantioselective couplings. The second part addresses stereoselective synthesis involving C(sp2)-H bonds, covering C-H activation in stereodiscriminant steps, planar chirality, and diastereoselective alkene formation. This resource highlights the diversity of stereogenic elements achievable through C-H activation methods. With its clear structure and expert insights, this book is essential for chemists in academia and industry, particularly in the pharmaceutical and agrochemical sectors, who are engaged in the rapidly evolving fields of organic synthesis and catalysis.

Achat du livre

• Année de publication: 2019
• Reliure: (rigide)