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We have detailed knowledge about microbial virulence factors. However, we are just beginning to understand how bacteria feed themselves during an infection and how they adapt their metabolism to the eukaryotic host. In the following volume, scientists who are focusing on pathogenic bacteria, bacterial physiology, regulation, analysis of the metabolome and the symbiosis between microbe and host, report on approaches used for analyzing metabolism during infections and the in-silico modeling of metabolic networks. Topics include general aspects of bacterial metabolism, global regulation of bacterial metabolism, the significance of RNA biology for bacterial metabolism and virulence, the metabolic adaption of pathogens to extra-cellular or intra-cellular lifestyles, the role of bio-films in bacterial communication and the transition from parasitic to endosymbiotic lifestyle. All articles are in English.
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Metabolism meets virulence, Jürgen Heesemann
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- 2010
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