SECTION 1: General aspects of vaccination§§1 A short history of vaccination 1§§2 Vaccine immunology 14§§3 The vaccine industry 33§§4 Vaccine manufacturing 44§§5 Evolution of adjuvants across the centuries 58§§6 Vaccine additives and manufacturing residuals in the United States:§§licensed vaccines 71§§7 Passive immunization 80§§8 General immunization practices 88§§SECTION 2: Licensed vaccines§§9 Adenovirus vaccines 113§§10 Anthrax vaccines 127§§11 Cholera vaccines 141§§12 Diphtheria toxoid 153§§13 Haemophilus influenzae vaccines 167§§14 Hepatitis A vaccines 183§§15 Hepatitis B vaccines 205§§16 Human papillomavirus vaccines 235§§17 Inactivated influenza vaccines 257§§18 Influenza vaccine-live 294§§19 Japanese encephalitis vaccines 312§§20 Measles vaccines 352§§21 Meningococcal vaccines 388§§22 Mumps vaccine 419§§23 Pertussis vaccines . 447§§24 Plague vaccines 493§§25 Pneumococcal conjugate vaccine and pneumococcal common protein vaccines 504§§26 Pneumococcal polysaccharide vaccines 542§§27 Poliovirus vaccine-inactivated . 573§§28 Poliovirus vaccine-live 598§§29 Rabies vaccines .646§§30 Rotavirus vaccines . 669§§31 Rubella vaccine 688§§32 Smallpox and vaccinia 718§§33 Tetanus toxoid 746§§34 Tick-borne encephalitis virus vaccines 773§§35 Tuberculosis vaccines 789§§36 Typhoid fever vaccines 812§§37 Varicella vaccine 837§§38 Yellow fever vaccine 870§§39 Zoster vaccine 969§§40 Combination vaccines 981§§SECTION 3: Vaccines in development and new vaccine strategies§§41 Biodefense and special pathogen vaccines 1008§§42 Therapeutic cancer vaccines 1018§§43 Cytomegalovirus vaccines 1032§§44 Dengue vaccines 1042§§45 Diarrhea caused by bacteria 1052§§46 Ebola vaccine 1060§§47 Epstein-Barr virus vaccines 1068§§48 Hepatitis C vaccines 1074§§49 Hepatitis E vaccines 1085§§50 Herpes simplex virus vaccines 1090§§51 Human immunodeficiency virus vaccines 1097§§52 Lyme disease vaccines 1122§§53 Malaria vaccines 1133§§54 Noninfectious disease vaccines 1138§§55 Respiratory syncytial virus and parainfluenza virus vaccines 1146§§56 Parasitic disease vaccines 1154§§57 Staphylococcus aureus vaccines 1161§§58 Streptococcus group A vaccines 1169§§59 Streptococcus group B vaccines 1176§§60 Technologies for making new vaccines 1182§§61 Alternative vaccine delivery methods 1200§§62 The development of gene-based vectors for immunization 1232§§SECTION 4: Vaccination of special groups§§63 Vaccination of immunocompromised hosts 1243§§64 Vaccination of human immunodeficiency virus- infected persons 1257§§65 Vaccines for international travel 1270§§66 Vaccines for health care personnel 1290§§SECTION 5: Public health and regulatory issues§§67 Immunization in the United States 1310§§68 Immunization in Europe . 1334§§69 Immunization in the Asia-Pacific region 1353§§70 Immunization in developing countries 1369§§71 Community immunity 1395§§72 Economic analyses of vaccine policies 1413§§73 Regulation and testing of vaccines 1427§§74 Regulation of vaccines in Europe 1447§§75 Regulation of vaccines in developing countries 1454§§76 Vaccine safety 1464§§77 Legal issues . 1481§§78 Ethics 1508§
Stanley A. Plotkin Livres




Mass vaccination
- 274pages
- 10 heures de lecture
Mass immunization acts as a rapid-response strategy in vaccination, effectively protecting populations through high coverage and induced herd immunity. However, like military operations, these campaigns require careful planning and logistical execution. Poorly conducted efforts can lead to failure or unintended consequences. This volume features insights from leading practitioners in the field. David Heymann and Bruce Aylward from WHO provide a foundational overview of mass immunization, blending theory with practice. Michael Lane shares his experiences from the successful smallpox eradication campaign, highlighting the role of mass vaccination. John Grabenstein and Remington Nevin discuss the application of mass immunization within the US military, drawing from their extensive expertise. Karen Noakes and David Salisbury illustrate the notable successes of mass immunization in the UK. Charles Vitek details the global control of clostridia responsible for diphtheria toxin, while Francis André shows the significant decline of Hepatitis A due to large-scale vaccination efforts. The French experience with Hepatitis B vaccination, discussed by François Denis and Daniel Levy-Bruhl, presents a more complex picture. Lastly, Benjamin Schwartz and Pascale Wortley recount the intricacies of annual influenza vaccination campaigns.
Preclinical and clinical development of new vaccines
- 290pages
- 11 heures de lecture
This publication covers all aspects of new vaccine development from the preclinical stage to licensing. It contains discussions about the preclinical testing which is necessary to obtain permission to test a new vaccine in clinical trials and to organize a clinical plan that will demonstrate the safety and efficacy of a new vaccine. In addition, some aspects of newer strategies, such as DNA immunization, are presented as well as a number of theoretical issues relating to vaccination, such as immunological correlates of protection, interference with immune responses, combination of vaccines, and the natural history of disease. Much attention is devoted to the proof of efficacy, a process which is both expensive and complicated. This volume is important reading for all scientists interested in vaccine development, especially those working in industry, government and public health authorities.
Spiralen - Symbol der Seelenreise. Zu den Abbildungen in diesem Buch§Leben lernen in Krisen. Vorwort zur 11., überarbeiteten und erweiterten Jubiläumsausgabe§Geleitwort des Ratsvorsitzenden der Evangelischen Kirche in Deutschland, EKD§Das Signal - Leserbrief 2001§1. Erfahrungen Betroffener und Angehöriger§2. Krisenverarbeitung als Lernproze- in 8 Spiralphasen§3. Begleitung und Glaube in Lebensgeschichten§4. Begleitende als Problem Betroffener§5. Theologisches zu Leiden und Leidensfähigkeit§Zusammenfassung§Anmerkungen§Literatur§Gegliederte Bibliographie der über 2000 Lebensgeschichten zur Krisenverarbeitung von 1900 bis zur Gegenwart mit Annotationen/Kurzinhalten§Alphabetisches Autoren-und Titelverzeichnis der über 2000 Lebensgeschichten zur Krisenverarbeitung von 1900 bis zur Gegenwart§Nachwort der Generalsekretäre des LWB und ÖRK§Verzeichnis der Abbildungen und Graphiken