Iwao Honjo Livres

The book critically reviews various methods for assessing cell proliferation, highlighting their significance in understanding normal and pathological tissues, especially in oncology. With the rise of new methodologies, it addresses the clinical relevance of these assessments as potential predictors of patient outcomes in malignancies. Contributors provide balanced insights into the advantages and disadvantages of each method while minimizing complex mathematical analyses, ensuring accessibility for readers interested in the clinical application of these techniques.

A Karger 'Publishing Highlights 1890–2015' title In recent years epoch-making tools like positron emission tomography (PET), magnetoencephalography (MEG) and functional magnetic resonance imaging have enabled us to finally investigate the enigma of language. This book discusses language from a primarily medical point of view. It reviews classical as well as recent studies on significant topics such as cortical mechanisms of language and the identification of receptive and perceptive speech areas. The interaction between brain areas for perception and production is discussed and a summary of the latest research in this field is provided. New findings on the role of the cerebellum and the supplementary motor area in speech perception are reported. Furthermore the latest up-to-date results of PET studies on users of cochlear implants that have immensely improved the understanding of development and plasticity of the cortical language networks, are presented. Otolaryngologists, neurologists, neurosurgeons, along with audiologists and speech therapists will find a wealth of new information in this publication, which provides them with contributions on the latest results on how the brain controls speech and language.

With a total of more than 10,000 operated patients worldwide, the implantation of cochlear devices has become the most effective technique in the treatment and rehabilitation of individuals with sensorineural hearing loss. The number of cochlear implant users, notably in Asian countries, is expected to grow significantly within the next few years. For this reason, more than 250 of the most experienced clinicians and researchers from 22 different countries gathered in Kyoto convey the latest knowledge on every aspect of this forward-looking discipline.The topics discussed in this volume range from basic sciences, anatomy and pathology to coding strategies, surgical techniques as well as pre- and postoperative complications. In a special section, the reader will find inspiring contributions on pediatric cochlear implantation. Particular emphasis is put on the comparison and evaluation of the various devices and on how different languages influence the performance of these implants. This publication will be an important source of information for anybody who is involved in the field of cochlear implantation.