This book presents an essential overview of beta-lactams and their medicinal value and use in the preparation of other biologically active compounds. Written by internationally respected authors, the individual chapters explore beta-lactams’ synthesis, their mechanism of formation, biological effects, and function as base materials for other heterocycles of major importance.
I. Ojima • E. S. Zuniga • J. D. Advances in the Use of Enantiopure β-Lactams for the Synthesis of Biologically Active Compounds of Medicinal Interests.- I. Fernández • Miguel A. β -Lactams from Fischer Carbene Scope, Limitations, and Reaction Mechanism.- Bablee Mandal • Basudeb Synthesis of β-Lactams Through Alkyne–Nitrone Cycloadditions.- T. T. Preparation of Bis-β-Lactams by Ketene–Imine Cycloadditions.- Edward The Chemistry and Biology of N -Thiolated β-Lactams.- Indrani Banik • Bimal K. Synthesis of β-Lactams and Their Chemical Manipulations Via Microwave-Induced Reactions.