Christian Oliver Kappe Livres

With the novice user in mind, this beginner's guide explains the basics behind microwave technology, evaluates available instruments and reaction modes, and provides practical hints for every eventuality. Includes 27 detailed protocols for often-used reactions. From the 1 Microwave Synthesis - An Introduction2 Microwave Theory3 Equipment Review4 Microwave Processing Techniques5 Starting With Microwave Chemistry6 Experimental Protocols6.1 General Small-Scale Sealed-Vessel Microwave Processing6.2 Reaction Optimization6.3 Library Generation6.4 Reaction Scale-Up6.5 Special Processing Techniques

The authors of this guide are experts on the use of microwaves for drug synthesis as well as having much experience in teaching courses held under the auspices of the American Chemical Society and the IUPAC. In this handy source of information for any practicing synthetic chemist they focus on common reaction types in medicinal chemistry, including solid-phase and combinatorial methods. They consider the underlying theory, latest developments in microwave applications and include a variety of examples from recent literature, as well as less common applications that are equally relevant for organic and medicinal chemists. An indispensable reference for researchers with an affinity to modern methods.