The research highlights the significant role of calcium antagonists in managing heart and vascular conditions linked to excessive calcium ion influx. By inhibiting this influx, these agents aim to prevent contractile hyperactivity in myocardial fibers and reduce vascular smooth muscle spasms. The study emphasizes the effectiveness of calcium antagonists in various vascular therapies, particularly in coronary and cerebral arteries, while acknowledging the importance of calcium ions in cardiac impulse generation and conduction.
