Gisela Dallenbach Hellweg Livres

For this second, expanded edition, most of the chapters have been extensively revised to include the latest immunohistochemical and molecular biological methods. With its clearly thought-out structure, this atlas enables the pathologist to find, classify, and differentially diagnose each disease. 280 top-quality illustrations - over half in full colour - are each accompanied by a description of the pathology of the disease, a summary of the causes, an explanation of its clinical importance, and treatment options, emphasising the importance of constant mutual co-operation with the attending gynaecologist. Microphotographs are arranged systematically according to morphology, and each is followed by a short description together with the aetiology and morphologic and differential diagnosis of the different conditions. Hemming Poulsen is head of the WHO Collaborating Center for the Histological Classification of tumours and the new chapter on neoplasms, for example, reflects this new WHO classification. Additional chapters cover gestational diseases as well as new findings in infertility and hormone replacement therapy.

The second edition of this atlas provides a detailed histopathological diagnosis of cervical disease emphasizing carcinogenesis, and correlating morphologic changes with clinical aspects. Instructions of how to obtain and handle tissue samples are followed by a description of the normal histology, of the action of steroid hormones on the cervix, and of the various forms of regeneration and inflammation. The section on etiology and pathogenesis of HPV-induced neoplasia has been enlarged to explain new insights into cellular and nuclear deregulation at the molecular level. A chapter on immunohistochemistry has been added which includes refined detection methods, e.g., with p16 for the early differential diagnosis of premalignant lesions. The latest advances in molecular biological research, with predictive subdivision of neoplasias, facilitate the choice of the proper therapy. All chapters – supported by over 20 new microphotographs – have been revised to include advances in the interpretation and management of cervical disease. The tumor nomenclature is adapted to the new WHO classification; the ICD-O code has been added. The reference list is updated with relevant publications.

Diese beiden Nachfolgebände der „ Gynäkologischen Endokrinologie “ (1987) signalisieren bereits im Titel die Erweiterung des Fachgebiets, die aus den zahlreichen Neuentwicklungen der letzten Jahre resultiert. Hierzu zählen z. B. der Nachweis und die Bedeutung neuer Hormone, Wachstumsfaktoren, neue Funktionsteste, die Therapie mit weiblichen Sexualhormonen, die Untersuchung von Umwelteinwirkungen sowie diagnostische und operative Techniken der Fertilitätschirurgie. Mit diesen beiden Büchern sind Sie umfassend über den aktuellen Kenntnisstand dieser Spezialgebiete informiert. Mit ihren zahlreichen Graphiken und Tabellen sowie ihrem ausgezeichneten Bildmaterial werden die Bände Gynäkologische Endokrinologie und Fortpflanzungsmedizin für Ärzte in der Klinik wie auch in der Praxis ein ständiger Begleiter sein.