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Chance, Development, and Aging

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  • 278pages
  • 10 heures de lecture

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In Chance, Development, and Aging , two leading biological gerontologists review and evaluate all of the available data to elucidate the respective roles played by genes and chance developmental events in determining the course of aging in individuals. The combination of genetic and externalenvironmental influences provides only an incomplete answer. Inbred laboratory animals, for example, exhibit a wide range of life spans despite having nearly identical genes and environments. Similarly, uncovering the genetic risks for Alzheimer's disease has not enabled doctors to predict withconfidence its onset and severity. This book argues that understanding chance events, specifically random variations during prenatal development, is essential for answering these questions. The book draws on the extensive research in developmental biology on random variations in form and function,while putting this research in a new context. The discussion sheds light on a range of questions, from understanding menopause to explaining why identical twins are not truly identical. The book will be invaluable for gerontologists, geneticists, developmental and reproductive biologists,physiologists, and a broad range of physicians and investigators in experimental medicine.

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Chance, Development, and Aging, Caleb Ellicott Finch, Thomas B. L. Kirkwood

Langue
Année de publication
2000
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(rigide),
État du livre
Bon
Prix
9,49 €

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Titre
Chance, Development, and Aging
Langue
Anglais
Publié
2000
Format
rigide
Pages
278
ISBN10
0195133617
ISBN13
9780195133615
Séries
Description
In Chance, Development, and Aging , two leading biological gerontologists review and evaluate all of the available data to elucidate the respective roles played by genes and chance developmental events in determining the course of aging in individuals. The combination of genetic and externalenvironmental influences provides only an incomplete answer. Inbred laboratory animals, for example, exhibit a wide range of life spans despite having nearly identical genes and environments. Similarly, uncovering the genetic risks for Alzheimer's disease has not enabled doctors to predict withconfidence its onset and severity. This book argues that understanding chance events, specifically random variations during prenatal development, is essential for answering these questions. The book draws on the extensive research in developmental biology on random variations in form and function,while putting this research in a new context. The discussion sheds light on a range of questions, from understanding menopause to explaining why identical twins are not truly identical. The book will be invaluable for gerontologists, geneticists, developmental and reproductive biologists,physiologists, and a broad range of physicians and investigators in experimental medicine.